Pancreatic Cancer

In: Science

Submitted By ewlord
Words 2232
Pages 9
The pancreas is a part of the endocrine system, and is located in the abdominal cavity surrounded by the liver, gallbladder, spleen, and stomach. The pancreas processes both exocrine and endocrine function. The exocrine function consists of the secretion of digestive enzymes into the duodenum through ducts. The enzymes digest starches and fats. The endocrine functions are a cluster of cells called the islets of Langerhans and only make up 2% of the pancreatic tissue. The islets of Langerhans is made up of three cells, alpha, beta, and delta.
There function is to secrete hormones and paracrine products. The most important hormones secreted are insulin, glucagon, and somatostatin. Alpha cells secrete glucagon, which increase blood glucose levels between meals. Beta cells secrete insulin, this is secreted when the level of glucose rises in the blood. Insulin stimulates cells to store nutrients to use between meals and at night to maintain blood glucose levels. Delta cells secrete somatostatin, after meals when blood glucose, fatty acids, and amino acids raise in the blood.

Pancreatic cancer is a highly malignant cancer. Tumors commonly originate from the epithelial cells of the pancreatic ductal system. This can happen in two ways, one that it has metastasized from a different part of the body, generally the lungs, breast, thyroid, kidneys, and skin. Second form is a primary tumor manly adenocarcinomas. Adenocarcinomas occur in secretory cells called glandular cells. These glandular cells line some organs within the endocrine system that make and release hormones in the lymphatic and venous system. Both system travel throughout the body and give opportunity to metastasis. The head of the pancreas is the most common place for cancer to form. Pancreatic cancer that starts on the tail and body metastasis to more places than if it…...

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